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How a Favored Migrant Route Became Invasive Species Superhighway to US

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The Darién Gap, long a perilous route for millions of migrants traveling north toward the United States, has also become a pathway for the northward spread of the New World screwworm—a parasitic fly now challenging decades of containment efforts.

The flesh-eating fly, whose larvae burrow into the wounds of living animals, has surged north through Central America since 2022, recently reaching the Mexican states of Oaxaca and Veracruz—roughly 700 miles from the Texas border. Scientists and federal officials now warn that the screwworm could cross into the U.S. as early as this summer if containment efforts falter.

For decades, the United States and Panama maintained a bi-national barrier to block the parasite at the Darién, using a program that dropped millions of sterilized screwworm flies over the jungle to prevent breeding. That system began unraveling in 2022, amid pandemic-era supply-chain disruptions and record human and animal movement through the region.

Between 2021 and 2024, more than 1.2 million migrants crossed the Darién, according to data from Panama's National Migration Service and UNHCR. The crossings peaked at 520,000 in 2023 before falling to 302,000 in 2024. U.S. officials believe that mass movement contributed to operational breakdowns in the region's screwworm control infrastructure.

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